Bridled by an autocratic mother, Charlotte Vale (Bette Davis) borders on a nervous breakdown. But when a psychiatrist (Claude Rains) persuades Charlotte to drastically change her life, she blossoms into a confident, self-possessed woman. Charlotte then takes a voyage, where she falls in love with the unhappily married Jerry (Paul Henreid). Though their romance is doomed, Charlotte finds solace in helping Jerry's emotionally unhinged daughter.

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