Dr. Francis Clay (Klaus Kinski) is the head doctor at an asylum that houses suicidal and mentally disturbed women. Hired by a wealthy socialite who's also a patient, Dr. Clay tries desperately to cure his female charges. But when a cloaked killer begins brutally murdering the asylum's patients, the "good" doctor finds himself numbered among the suspects. Liberal doses of nudity, gore and Kinski's terminal weirdness inform this Italian movie.