Lisa's (Rachel McAdams) fear of flying always makes her edgy, but what awaits her on her next flight -- a red-eye to Miami -- is far worse. After takeoff, the man sitting next to her (Cillian Murphy) divulges the actual reason he's there: to kill a prominent businessman, with Lisa's help. If she fails to aid him, her father will be killed. Now, Lisa is on a desperate and dangerous quest to stop him. Wes Craven directs this tense thriller.