Watts later relocated to Hollywood, but her early screen efforts failed to impress audiences or critics, except for her turn as Lori Petty's pal in the 1995 cult flick Tank Girl. It was a breakthrough dual role in director David Lynch's surreal mystery Mulholland Drive (2001) that finally put Watts on the "A" list and earned her numerous industry honors.
The blond beauty delivered an even more riveting performance in the 2003 multilayered drama 21 Grams and was rewarded with an Oscar nod for Best Actress. Her other films of note include the 2005 remake of King Kong and the ensemble drama Mother and Child (2009), which brought Watts an Independent Spirit Award nomination for her supporting work.