In the early 1990s, Perez parlayed her motormouth persona into featured roles in a number of films, including White Man Can't Jump (opposite Woody Harrelson) and Jim Jarmusch's Night on Earth. Playing against type -- and earning an Oscar nomination for her efforts -- Perez next wowed audiences and critics alike with her portrayal of a tormented plane crash survivor in Peter Weir's Fearless (1993).
More recent films for Perez include Riding in Cars with Boys (opposite Drew Barrymore) and the 2005 HBO movie Lackawanna Blues.